Open fracture wound infections caused by Aeromonas species
Tung-Lung Wu, Chung-Da Wu, Chung-Hsing Yu, Chi-Chou Tseng, Huan-Tee Chan, Po-Yih Chen, Wei-Ming Chen, Wei-Ting Lin
Background: The knowledge about Aeromonas infections following open fracture is limited, so the aim of this study was to the clinical characteristics of patients with open fracture wound infections caused by Aeromonas species. Materials and Methods: From 2009 to 2012, patients with open fracture wound infections caused by Aeromonas species were identified from a computerized database of a regional hospital and a medical center in southern Taiwan. The medical records of these patients were retrospectively reviewed. Results: A total of 27 patients with an open wound infections due to Aeromonas species were identified. The patients ranged in age from 18 to 77 years (mean, 49.6 years). Active cancer (n = 3, 11.1%) was the most common underlying disease. About 26% (n = 7) of the patients had a history of exposure to aqueous environments prior to infection. Eight patients presented with shock, but only one patient presented with hemorrhagic bullae. The majority (n = 22, 82%) of patients had polymicrobial infections. Among six patients who required amputation, three did not receive appropriate antibiotic initially, and three cases had initial presentations of septic shocks. The overall in-hospital mortality was 3.7%. Conclusions: Aeromonas species should be considered important causative pathogens of the open wound infections and most infections are polymicrobial. The outcome was poor, especially for patients receiving inappropriate initial antibiotic or presenting with shock.