E-ISSN 2149-2018
 

Original Research (Original Article) 


Effect of camel milk supplementation in management of gastric ulcer

Aminu Lailaba Abubakar, abdullahi Dandare, Shamsudeen Umar Dandare, Sulaiman Rabiu, Abdulqadir Sule Ibrahim, Saifullahi Armaya'u.

Abstract
BACKGROUND: Gastric ulcer is one of the major causes of morbidity globally. It is prevalent in Nigeria, and more frequent among the lowest income group; this is primarily linked to their standard of living and constant use of non-steroidal anti-inflammatory drugs. The use of camel milk in the treatment of many diseases has long been established.
OBJECTIVE: This study was designed to evaluate the potentials of camel milk in the treatment gastric ulceration.
METHODS: Albino rats weighed 120-150g, were divided into four groups of five rats each. Group I: negative control, group II: positive control, group III: ethanol induced gastric ulcer rats supplemented with camel milk, group IV: ethanol induced gastric ulcer rats orally dosed with omeprazole.
RESULTS: The results of this study revealed that WBC, RBC, HBC, PCV, MCV, and PLT decreased significantly (P<0.05) in ethanol induced ulcer group compared to other groups. There were no significant differences (P>0.05) in MCH and MCHC level for all the groups investigated. The levels of antioxidant enzymes (CAT and SOD), and vitamins (A, C, and E) were significantly improved toward normal (P<0.05) due camel milk supplementation. The histopathological analysis of the stomach tissue indicates preserved transnural architecture with clearly defined mucosa, sub-mucosa, and muscularis propria in camel milk supplemented group and omeprazole treated group.
CONCLUTION: These results demonstrated the potential use of camel milk in reversing the damaging effect of ethanol induced gastric ulcer and alteration of some biochemical parameters. Hence camel milk could be use as a dietary supplement for managing gastric ulcer.

Key words: Camel milk, Ethanol, Gastric ulcer, Omeprazole, Transmural architecture.


 
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Pubmed Style

Abubakar AL, Dandare a, Dandare SU, Rabiu S, Ibrahim AS, Armayau S, . Effect of camel milk supplementation in management of gastric ulcer . Appl Med Res. 2018; 4(1): 12-17. doi:10.5455/amr.20180724045336


Web Style

Abubakar AL, Dandare a, Dandare SU, Rabiu S, Ibrahim AS, Armayau S, . Effect of camel milk supplementation in management of gastric ulcer . http://www.ejmamr.com/?mno=302643247 [Access: December 15, 2018]. doi:10.5455/amr.20180724045336


AMA (American Medical Association) Style

Abubakar AL, Dandare a, Dandare SU, Rabiu S, Ibrahim AS, Armayau S, . Effect of camel milk supplementation in management of gastric ulcer . Appl Med Res. 2018; 4(1): 12-17. doi:10.5455/amr.20180724045336



Vancouver/ICMJE Style

Abubakar AL, Dandare a, Dandare SU, Rabiu S, Ibrahim AS, Armayau S, . Effect of camel milk supplementation in management of gastric ulcer . Appl Med Res. (2018), [cited December 15, 2018]; 4(1): 12-17. doi:10.5455/amr.20180724045336



Harvard Style

Abubakar, A. L., Dandare, a. ., Dandare, S. U., Rabiu, S. ., Ibrahim, A. S., Armayau, S. . & (2018) Effect of camel milk supplementation in management of gastric ulcer . Appl Med Res, 4 (1), 12-17. doi:10.5455/amr.20180724045336



Turabian Style

Abubakar, Aminu Lailaba, abdullahi Dandare, Shamsudeen Umar Dandare, Sulaiman Rabiu, Abdulqadir Sule Ibrahim, Saifullahi Armayau, and . 2018. Effect of camel milk supplementation in management of gastric ulcer . Applied Medical Research, 4 (1), 12-17. doi:10.5455/amr.20180724045336



Chicago Style

Abubakar, Aminu Lailaba, abdullahi Dandare, Shamsudeen Umar Dandare, Sulaiman Rabiu, Abdulqadir Sule Ibrahim, Saifullahi Armayau, and . "Effect of camel milk supplementation in management of gastric ulcer ." Applied Medical Research 4 (2018), 12-17. doi:10.5455/amr.20180724045336



MLA (The Modern Language Association) Style

Abubakar, Aminu Lailaba, abdullahi Dandare, Shamsudeen Umar Dandare, Sulaiman Rabiu, Abdulqadir Sule Ibrahim, Saifullahi Armayau, and . "Effect of camel milk supplementation in management of gastric ulcer ." Applied Medical Research 4.1 (2018), 12-17. Print. doi:10.5455/amr.20180724045336



APA (American Psychological Association) Style

Abubakar, A. L., Dandare, a. ., Dandare, S. U., Rabiu, S. ., Ibrahim, A. S., Armayau, S. . & (2018) Effect of camel milk supplementation in management of gastric ulcer . Applied Medical Research, 4 (1), 12-17. doi:10.5455/amr.20180724045336





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