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Appl Med Res. 2015; 1(3): 104-108

doi: 10.5455/amr.20150412074909

Cutaneous tuberculosis: a clinicopathological study of 50 cases from a tertiary care referral hospital

Rajpal Singh Punia, Phiza Aggarwal, Reetu Kundu, Harsh Mohan, Mala Bhalla, Deepak Aggarwal.

Cited by (1)

Abstract
Background: Tuberculosis is a health problem worldwide. Cutaneous tuberculosis comprises a small fraction of all clinical forms of tuberculosis.
Objective: The purpose of this study was to assess the disease pattern of cutaneous tuberculosis in an Asian country.
Materials and Methods: Fifty cases of cutaneous tuberculosis were diagnosed on histopathology in a tertiary care hospital over a period of seven years. Relevant clinical details and available laboratory findings were correlated.
Results: The patients ranged from 4-78 years with 26 males and 24 females. Neck was the most common site. Twenty two (44%) cases presented with erythematous plaques followed by papules in nine (18%) cases. Classical epithelioid cell granulomas with Langhans giant cells were found in 46 (92%) patients, while caseation necrosis was seen in 18 (36%). On Ziehl-Neelsen staining, acid fast bacilli were demonstrated in six (12%). Twenty four (48%) patients were diagnosed lupus vulgaris, 11 (22%) scrofuloderma, four (8%) tuberculosis verrucosa cutis, one (2%) tuberculosis cutis orificialis and 10 (20%) tuberculosis non specific type.
Conclusion: Lupus vulgaris is most common presentation of cutaneous tuberculosis. Caseating epithelioid cell granulomas with or without positive Ziehl-Neelsen stain constitute the classical picture. Knowledge of different histopathological features and their variation is important for an accurate diagnosis.

Key words: Cutaneous, tuberculosis, histopathology, granuloma, Ziehl-Neelsen stain

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REFERENCES

1. World Health Organization (WHO). Global Tuberculosis Report. Geneva: WHO; 2013.

2. Hamada M, Urabe K, Moroi Y, Miyazaki M, Furue M. Epidemiology of cutaneous tuberculosis in Japan: A retrospective study from 1906 to 2002. Int J Dermatol 2004;43:727-31. [DOI via Crossref] [Pubmed]

3. Kumar B, Kaur S. Pattern of cutaneous tuberculosis in North India. Indian J Dermatol Venereol Leprol 1986;52:203-7.

4. Sehgal VN, Srivastava G, Khurana VK, Sharma VK, Bhalla P, Beohar PC. An appraisal of epidemiologic, clinical, bacteriologic, histopathologic, and immunologic parameters in cutaneous tuberculosis. Int J Dermatol 1987;26:521-6. [DOI via Crossref] [Pubmed]

5. Banerjee B. Tuberculosis of the skin and its relation with pulmonary tuberculosis. Indian J Dermatol 1957;2:69.

6. Moschella S, Cropley T. Diseases of the mononuclear phagocytic system (the so called reticulo endothelial system). In: Moschella S, Hurley HJ, editors. Textbook of Dermatology. Philadelphia: W.B. Saunders Company; 1992. p. 1031-3.

7. Yasmeen N, Kanjee A. Cutaneous tuberculosis: A three year prospective study. J Pak Med Assoc 2005;55:10-2. [Pubmed]

8. Dubrous P, Alaoui H, N'Dounga Mikolo B, Koeck JL. Diagnosis of tuberculosis in developing countries: New perspectives. Med Trop (Mars) 2009;69:618-28.

9. Gopinathan R, Pandit D, Joshi J, Jerajani H, Mathur M. Clinical and morphological variants of cutaneous tuberculosis and its relation to Mycobacterium species. Indian J Med Microbiol 2001;19:193-6. [Pubmed]

10. Beyt BE Jr, Ortbals DW, Santa Cruz DJ, Kobayashi GS, Eisen AZ, Medoff G. Cutaneous mycobacteriosis: Analysis of 34 cases with a new classification of the disease. Medicine (Baltimore) 1981;60:95-109. [DOI via Crossref]

11. Dwari BC, Ghosh A, Paudel R, Kishore P. A clinicoepidemiological study of 50 cases of cutaneous tuberculosis in a tertiary care teaching hospital in pokhara, Nepal. Indian J Dermatol 2010;55:233-7. [DOI via Crossref] [Pubmed] [PMC Free Fulltext]

12. Chaudhari N, Talaniker H, Deshmukh P, Gupta S. A clinicopathological study of cutaneous tuberculosis at Pune district, Maharashtra. Int J Pharm Biomed Sci 2012;3:181-3.

13. Puri N. A clinical and histopathological profile of patients with cutaneous tuberculosis. Indian J Dermatol 2011;56:550-2. [DOI via Crossref] [Pubmed] [PMC Free Fulltext]

14. GarcÃa-RodrÃguez JF, Monteagudo-SÃ¡nchez B, Mari-o-Callejo A. Cutaneous tuberculosis: A 15-year descriptive study. Enferm Infecc Microbiol Clin 2008;26:205-11. [DOI via Crossref]

15. Hajlaoui K, Fazaa B, Zermani R, Zeglaoui F, El Fekib N, Ezzine N, et al. Cutaneous tuberculosis. A review of 38 cases. Tunis Med 2006;84:537-41. [Pubmed]

16. Sultana A, Bhuiyan MS, Haque A, Bashar A, Islam MT, Rahman MM. Pattern of cutaneous tuberculosis among children and adolescent. Bangladesh Med Res Counc Bull 2012;38:94-7. [Pubmed]

17. HernÃ¡ndez Solis A, Herrera GonzÃ¡lez NE, Cazarez F, Mercadillo PÃ©rez P, Olivera Diaz HO, Escobar-Gutierrez A, et al. Skin biopsy: A pillar in the identification of cutaneous Mycobacterium tuberculosis infection. J Infect Dev Ctries 2012;6:626-31. [Pubmed]

18. Patra A, Gharami R, Banerjee P. A profile of cutaneous tuberculosis. Indian J Dermatol 2006;51:105-7. [DOI via Crossref]

19. Chong LY, Lo KK. Cutaneous tuberculosis in Hong Kong: A 10-year retrospective study. Int J Dermatol 1995;34:26-9. [DOI via Crossref]

20. Wong KO, Lee KP, Chiu SF. Tuberculosis of the skin in Hong Kong. (A review of 160 cases). Br J Dermatol 1968;80:424-9. [DOI via Crossref] [Pubmed]

21. Santos JB, Figueiredo AR, Ferraz CE, Oliveira MH, Silva PG, Medeiros VL. Cutaneous tuberculosis: Epidemiologic, etiopathogenic and clinical aspects - Part I. An Bras Dermatol 2014;89:219-28. [DOI via Crossref] [Pubmed] [PMC Free Fulltext]

22. Grayson W. Infectious diseases of the skin. In: Calonje E, Brenn T, Lazar A, McKee PH, editors. McKee's Pathology of the Skin. 4th ed. China: Elsevier Limited; 2012. p. 760-895. [DOI via Crossref]

This Article Cited By the following articles

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How to Cite this Article

Pubmed Style

Rajpal Singh Punia, Phiza Aggarwal, Reetu Kundu, Harsh Mohan, Mala Bhalla, Deepak Aggarwal. Cutaneous tuberculosis: a clinicopathological study of 50 cases from a tertiary care referral hospital. Appl Med Res. 2015; 1(3): 104-108. doi:10.5455/amr.20150412074909

Web Style

Rajpal Singh Punia, Phiza Aggarwal, Reetu Kundu, Harsh Mohan, Mala Bhalla, Deepak Aggarwal. Cutaneous tuberculosis: a clinicopathological study of 50 cases from a tertiary care referral hospital. http://www.ejmamr.com/?mno=183719 [Access: August 19, 2019]. doi:10.5455/amr.20150412074909

AMA (American Medical Association) Style

Rajpal Singh Punia, Phiza Aggarwal, Reetu Kundu, Harsh Mohan, Mala Bhalla, Deepak Aggarwal. Cutaneous tuberculosis: a clinicopathological study of 50 cases from a tertiary care referral hospital. Appl Med Res. 2015; 1(3): 104-108. doi:10.5455/amr.20150412074909

Vancouver/ICMJE Style

Rajpal Singh Punia, Phiza Aggarwal, Reetu Kundu, Harsh Mohan, Mala Bhalla, Deepak Aggarwal. Cutaneous tuberculosis: a clinicopathological study of 50 cases from a tertiary care referral hospital. Appl Med Res. (2015), [cited August 19, 2019]; 1(3): 104-108. doi:10.5455/amr.20150412074909

Harvard Style

Rajpal Singh Punia, Phiza Aggarwal, Reetu Kundu, Harsh Mohan, Mala Bhalla, Deepak Aggarwal (2015) Cutaneous tuberculosis: a clinicopathological study of 50 cases from a tertiary care referral hospital. Appl Med Res, 1 (3), 104-108. doi:10.5455/amr.20150412074909

Turabian Style

Rajpal Singh Punia, Phiza Aggarwal, Reetu Kundu, Harsh Mohan, Mala Bhalla, Deepak Aggarwal. 2015. Cutaneous tuberculosis: a clinicopathological study of 50 cases from a tertiary care referral hospital. Applied Medical Research, 1 (3), 104-108. doi:10.5455/amr.20150412074909

Chicago Style

Rajpal Singh Punia, Phiza Aggarwal, Reetu Kundu, Harsh Mohan, Mala Bhalla, Deepak Aggarwal. "Cutaneous tuberculosis: a clinicopathological study of 50 cases from a tertiary care referral hospital." Applied Medical Research 1 (2015), 104-108. doi:10.5455/amr.20150412074909

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Rajpal Singh Punia, Phiza Aggarwal, Reetu Kundu, Harsh Mohan, Mala Bhalla, Deepak Aggarwal (2015) Cutaneous tuberculosis: a clinicopathological study of 50 cases from a tertiary care referral hospital. Applied Medical Research, 1 (3), 104-108. doi:10.5455/amr.20150412074909

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