E-ISSN 2149-2018
 

Original Research 


Effect of a methanol extract of Allium cepa Linn. on incisional wound healing in alloxan-induced diabetic mice

David Emery Tsala, Mendimi Nkodo Joseph, Tatsimo Simplice, Nnanga Nga, Edmond Jacques, Miaffo David.

Abstract
Aim: The objective of the present study was to evaluate the wound healing effect of a methanol extract of Allium cepa Linn. in vivo. Materials and Methods: The healing activity was studied using incision wound on diabetes suppressed wound healing rodent model. Results: Data recorded exhibited a significant improvement of the blood glucose level and scare breaking strength in diabetic mice at 300 and 400 mg/kg onion extract. Histological examination of the general morphology of wounds of extract treated group has shown a normal histological pattern of healthy skin at the same doses. Conclusion: This study illustrated an excellent potential of the onion consumption on dermal wound healing in diabetic patients, with a tentative mechanism of action related to tensile strength improvement and anti-hyperglycemic effect.

Key words: Allium cepa, diabetes, tensile strength


 
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How to Cite this Article
Pubmed Style

David Emery Tsala, Mendimi Nkodo Joseph, Tatsimo Simplice, Nnanga Nga, Edmond Jacques, Miaffo David. Effect of a methanol extract of Allium cepa Linn. on incisional wound healing in alloxan-induced diabetic mice. Appl Med Res. 2015; 1(3): 90-93. doi:10.5455/amr.20150427021827


Web Style

David Emery Tsala, Mendimi Nkodo Joseph, Tatsimo Simplice, Nnanga Nga, Edmond Jacques, Miaffo David. Effect of a methanol extract of Allium cepa Linn. on incisional wound healing in alloxan-induced diabetic mice. http://www.ejmamr.com/?mno=183400 [Access: December 15, 2018]. doi:10.5455/amr.20150427021827


AMA (American Medical Association) Style

David Emery Tsala, Mendimi Nkodo Joseph, Tatsimo Simplice, Nnanga Nga, Edmond Jacques, Miaffo David. Effect of a methanol extract of Allium cepa Linn. on incisional wound healing in alloxan-induced diabetic mice. Appl Med Res. 2015; 1(3): 90-93. doi:10.5455/amr.20150427021827



Vancouver/ICMJE Style

David Emery Tsala, Mendimi Nkodo Joseph, Tatsimo Simplice, Nnanga Nga, Edmond Jacques, Miaffo David. Effect of a methanol extract of Allium cepa Linn. on incisional wound healing in alloxan-induced diabetic mice. Appl Med Res. (2015), [cited December 15, 2018]; 1(3): 90-93. doi:10.5455/amr.20150427021827



Harvard Style

David Emery Tsala, Mendimi Nkodo Joseph, Tatsimo Simplice, Nnanga Nga, Edmond Jacques, Miaffo David (2015) Effect of a methanol extract of Allium cepa Linn. on incisional wound healing in alloxan-induced diabetic mice. Appl Med Res, 1 (3), 90-93. doi:10.5455/amr.20150427021827



Turabian Style

David Emery Tsala, Mendimi Nkodo Joseph, Tatsimo Simplice, Nnanga Nga, Edmond Jacques, Miaffo David. 2015. Effect of a methanol extract of Allium cepa Linn. on incisional wound healing in alloxan-induced diabetic mice. Applied Medical Research, 1 (3), 90-93. doi:10.5455/amr.20150427021827



Chicago Style

David Emery Tsala, Mendimi Nkodo Joseph, Tatsimo Simplice, Nnanga Nga, Edmond Jacques, Miaffo David. "Effect of a methanol extract of Allium cepa Linn. on incisional wound healing in alloxan-induced diabetic mice." Applied Medical Research 1 (2015), 90-93. doi:10.5455/amr.20150427021827



MLA (The Modern Language Association) Style

David Emery Tsala, Mendimi Nkodo Joseph, Tatsimo Simplice, Nnanga Nga, Edmond Jacques, Miaffo David. "Effect of a methanol extract of Allium cepa Linn. on incisional wound healing in alloxan-induced diabetic mice." Applied Medical Research 1.3 (2015), 90-93. Print. doi:10.5455/amr.20150427021827



APA (American Psychological Association) Style

David Emery Tsala, Mendimi Nkodo Joseph, Tatsimo Simplice, Nnanga Nga, Edmond Jacques, Miaffo David (2015) Effect of a methanol extract of Allium cepa Linn. on incisional wound healing in alloxan-induced diabetic mice. Applied Medical Research, 1 (3), 90-93. doi:10.5455/amr.20150427021827





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