E-ISSN 2149-2018
 

Original Research 


In Vivo Antioxidant Activities of Combretum platypterum (Welw.) Hutch. and Combretum racemosum P. Beauv. (Combretaceae)

MacDonald Idu, Dickson Uwaya, Oghale Ovuakporie-Uvo.

Abstract
Aim: The aim of this study was to evaluate the in vivo antioxidant effect of the aqueous leaf extract of both plants. Methods: Seven groups of 4 animals each were used. Groups 1 3 were administered C. platypterum extract at various doses. Groups 4 6 were administered C. racemosum extract while group 7 received distilled water. The animals were sacrificed after 21 days using chloroform as anesthesia. Vital organs; hearts, livers and kidneys were isolated and homogenized for antioxidant assays. Results: C. platypterum significantly (P<0.05) increased the level of SOD and peroxidase in the heart at (200 and 400) mg/kg. SOD level was also increased in the liver at 400 mg/kg and peroxidase in the kidney at all doses improved. C. racemosum significantly (P<0.05) increased the level of peroxidase in the kidney at doses (100, 200 and 400) mg/kg. MDA and catalase level were unaffected by aqueous leaf extracts of both plants. In vivo antioxidant activity of C. platypterum was more in C. racemosum. However, there was a marked boost of peroxidase in the kidney of animals treated with C. racemosum. Conclusion: C. platypterum demonstrates superior antioxidant activity in the heart and liver compared to C. racemosum <div style="display:none;"> <a href="http://escortbayanlara.com" target="_blank">Escort Bayanlar</a> </div>

Key words: Combretum platypterum, Combretum racemosum, in vivo antioxidant.


 
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How to Cite this Article
Pubmed Style

MacDonald Idu, Dickson Uwaya, Oghale Ovuakporie-Uvo. In Vivo Antioxidant Activities of Combretum platypterum (Welw.) Hutch. and Combretum racemosum P. Beauv. (Combretaceae). Appl Med Res. 2016; 2(3): 50-55. doi:10.5455/amr.20160818035633


Web Style

MacDonald Idu, Dickson Uwaya, Oghale Ovuakporie-Uvo. In Vivo Antioxidant Activities of Combretum platypterum (Welw.) Hutch. and Combretum racemosum P. Beauv. (Combretaceae). http://www.ejmamr.com/?mno=225803 [Access: December 15, 2018]. doi:10.5455/amr.20160818035633


AMA (American Medical Association) Style

MacDonald Idu, Dickson Uwaya, Oghale Ovuakporie-Uvo. In Vivo Antioxidant Activities of Combretum platypterum (Welw.) Hutch. and Combretum racemosum P. Beauv. (Combretaceae). Appl Med Res. 2016; 2(3): 50-55. doi:10.5455/amr.20160818035633



Vancouver/ICMJE Style

MacDonald Idu, Dickson Uwaya, Oghale Ovuakporie-Uvo. In Vivo Antioxidant Activities of Combretum platypterum (Welw.) Hutch. and Combretum racemosum P. Beauv. (Combretaceae). Appl Med Res. (2016), [cited December 15, 2018]; 2(3): 50-55. doi:10.5455/amr.20160818035633



Harvard Style

MacDonald Idu, Dickson Uwaya, Oghale Ovuakporie-Uvo (2016) In Vivo Antioxidant Activities of Combretum platypterum (Welw.) Hutch. and Combretum racemosum P. Beauv. (Combretaceae). Appl Med Res, 2 (3), 50-55. doi:10.5455/amr.20160818035633



Turabian Style

MacDonald Idu, Dickson Uwaya, Oghale Ovuakporie-Uvo. 2016. In Vivo Antioxidant Activities of Combretum platypterum (Welw.) Hutch. and Combretum racemosum P. Beauv. (Combretaceae). Applied Medical Research, 2 (3), 50-55. doi:10.5455/amr.20160818035633



Chicago Style

MacDonald Idu, Dickson Uwaya, Oghale Ovuakporie-Uvo. "In Vivo Antioxidant Activities of Combretum platypterum (Welw.) Hutch. and Combretum racemosum P. Beauv. (Combretaceae)." Applied Medical Research 2 (2016), 50-55. doi:10.5455/amr.20160818035633



MLA (The Modern Language Association) Style

MacDonald Idu, Dickson Uwaya, Oghale Ovuakporie-Uvo. "In Vivo Antioxidant Activities of Combretum platypterum (Welw.) Hutch. and Combretum racemosum P. Beauv. (Combretaceae)." Applied Medical Research 2.3 (2016), 50-55. Print. doi:10.5455/amr.20160818035633



APA (American Psychological Association) Style

MacDonald Idu, Dickson Uwaya, Oghale Ovuakporie-Uvo (2016) In Vivo Antioxidant Activities of Combretum platypterum (Welw.) Hutch. and Combretum racemosum P. Beauv. (Combretaceae). Applied Medical Research, 2 (3), 50-55. doi:10.5455/amr.20160818035633





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